News for Healthier Living

Stimulating Fat Cells with GIP Receptor Has Potential to Treat Obesity

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study. Published in Cell Metabolism, the findings highlight the potential of GIPR - a protein thought of as a minor player in a class of popular weight-loss drugs - to have its own starring role in therapies to fight obesity.

January 6, 2025


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